Non-Anemic Iron Deficiency: Correlations Between Symptoms and Iron Status Parameters

    Julien Beatrix, Claire Piales, Pauline Berland, Eric Marchiset, Laurent Gerbaud, M. Ruivard
    TLDR Low iron levels can cause hair loss and restless legs in non-anemic women.
    This study examined the correlation between symptoms and iron status in 554 non-anemic menstruating women aged 18–50 years. It found that iron deficiency, indicated by low serum ferritin (SF) levels, was significantly associated with recent hair loss and restless legs syndrome. Specifically, hair loss was more common in women with SF levels ≤20 µg/l, while restless legs syndrome was linked to SF levels ≤50 µg/l. The study suggested that non-anemic iron deficiency could affect quality of life, and recommended considering iron supplementation if these symptoms were reported in primary care.
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