A Novel Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth via Induction of VEGF Production
January 2017
Toshio Nakamura, Yamamura Haruo, Park Kyungho, Yoshikazu Uchida, Horie Noriko, Mujo Kim, Satoshi Itami
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Peptides, specifically GHK-Cu, are being considered for hairgrowth benefits, such as increasing blood flow to the scalp and preventing hair follicle shrinkage. A user reported starting GHK-Cu after hearing it made a friend's hair thicker.
The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.
Peptides like GHK-Cu are discussed for hair regrowth, with mixed results; some users report no regrowth, while others notice thicker hair. Topical application is common, and proper sourcing and mixing are emphasized.
KPV, apeptide patented by L'Oreal, may promote hairgrowth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hairgrowth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
A user is exploring VEGF gene therapy to enhance hair transplant results, considering measuring hair shaft diameter and growth rate. Suggestions include using phototrichograms and possibly adding PRP, though its effectiveness is uncertain.