Oclacitinib Treatment and Surgical Management in a Case of Periocular Eosinophilic Furunculosis and Vasculitis with Secondary Eyelid Fusion in a Diabetic Cat

A 10-year-old diabetic British Shorthair cat with periocular eosinophilic furunculosis and vasculitis experienced eyelid fusion, which was unresponsive to glucocorticoids due to diabetes. Oclacitinib, a JAK-1 inhibitor not typically used in cats, was administered, resulting in rapid remission of symptoms and no recurrence for 17 months. Surgical intervention was necessary to correct eyelid fusion and restore normal blinking. This case suggests oclacitinib as a potential alternative treatment for inflammatory conditions in cats when traditional therapies are contraindicated, though careful consideration is needed due to potential side effects in diabetic cats.