Organoids Producing Materials

This review discusses the potential of self-organizing tissues, such as organoids, to sustainably produce advanced materials, addressing issues like resource scarcity and global warming. It highlights the use of developmental biology as a manufacturing process, exemplified by spider silk production through self-organized silk glands. The review emphasizes the superior mechanical properties and biodegradability of materials produced by biological systems using renewable resources. Hair-bearing organoids, derived from induced pluripotent stem cells, illustrate the concept of growing both materials and their production units. Challenges in expanding organoid research and scaling production are addressed, with proposed solutions and exploration of synthetic and hybrid approaches. The review underscores the promise of material-producing organoids for sustainable, high-value products and encourages interdisciplinary collaboration to tackle global challenges.