TLDR Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.
In 1992, there was growing interest in diagnosing and treating polycystic ovarian syndrome (PCOS) in adolescents due to its association with menstrual irregularities, hirsutism, and acne, which are significant concerns for young females. The review highlighted that early diagnosis and treatment might prevent the progression to the classical adult form of PCOS. Despite being recognized for over 85 years, the etiology of PCOS was still unclear. The review discussed the physiology of androgens and hair follicles, the potential causes of PCOS, and the often accompanying conditions of hyperprolactinemia and hyperinsulinemia. It emphasized the importance of careful diagnosis and treatment approaches tailored to the unique challenges faced by adolescents with PCOS.
5 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” Nuclear AR levels give better insight into hormone effects in skin conditions.
130 citations
,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
100 citations
,
April 1990 in “The Journal of Clinical Endocrinology & Metabolism” The ovary mainly causes high testosterone in PCO, while the adrenal gland is the main source in IH.
13 citations
,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
5 citations
,
July 1987 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” The treatment temporarily improved symptoms of hyperandrogenism in adolescents.
75 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
27 citations
,
May 1976 in “PubMed” Ovarian wedge resection helped regulate menstrual cycles but didn't significantly change hormone levels or hair growth in polycystic ovary syndrome.