Perforating Folliculitis: A Transepidermal Elimination Disorder

January 2026 in “ JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH ”

Balakumaran ., Sukanya Mathupal, G Gowripriya, Madhumita Rajmohan

perforating folliculitis transepidermal elimination doxycycline keratolytic-based emollient

TLDR A 62-year-old man with diabetes and kidney disease had itchy skin lesions diagnosed as perforating folliculitis, treated with medication and skin care.

A 62-year-old male with a history of uncontrolled diabetes and chronic kidney disease presented with dark, raised, itchy lesions on his limbs, diagnosed as perforating folliculitis. Histopathological examination showed dilated hair follicles with basophilic debris and transepithelial extrusion of collagen, confirming the diagnosis. Treatment included managing creatinine levels, glycaemic control, and a 7-day course of Doxycycline, Bilastine, and a keratolytic-based emollient. The patient's follow-up was not possible, so further clinical progression was not assessed.

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