Exposure to Non-Persistent Pesticides and Sexual Maturation of Spanish Adolescent Males

The study investigated the impact of non-persistent pesticide exposure on the sexual maturation of 201 Spanish adolescent males aged 14-17 years. It found that higher concentrations of certain pesticide metabolites, such as DETP and TCPy, were linked to lower odds of reaching advanced stages of genital development and gonadal maturity, respectively. Conversely, 1-NPL was associated with higher odds of reaching an advanced adrenal stage but lower odds of achieving mature testicular volume. These findings suggested that exposure to specific pesticides might be associated with delayed sexual maturity in adolescent males.