Pharmacologic Properties of Minoxidil: A New Hypotensive Agent
March 1973
in “
PubMed
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TLDR Minoxidil is a new drug that lowers blood pressure.
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6 / 1000+ resultscommunity Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule
in Research 83 upvotes 1 month ago Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.
community Low-Dose Oral Minoxidil Does Not Significantly Affect BP
in Minoxidil 178 upvotes 1 year ago Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.
community Oral minoxidil hypertension effect vanishes when mixed with water
in General 27 upvotes 1 month ago Mixing 2.5mg of minoxidil powder with 150ml of water seems to eliminate its blood pressure effects, causing only a brief 20-second hypertension. The reason for this effect is unclear.
community Minoxidil is a 5ar inhibitor according to research
in Research/Science 148 upvotes 5 months ago Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.
community (comment) providing facts on people talking nonsense about minoxidil and BP-medicaton in general
in Research/Science 16 upvotes 2 years ago Minoxidil is used for hair loss and sometimes for high blood pressure, but it's outdated for the latter. For high blood pressure, it's combined with a beta blocker and diuretic to manage side effects.
community Being Safe on Oral Minoxidil: tl;dr on the literature.
in Research/Science 51 upvotes 1 year ago Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.
Related Research
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research Minoxidil Prevents MDMA-Induced Serotonin Depletions: Role of Mitochondrial ATP-Sensitive Potassium Channels, Akt, and ERK
22 citations , February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.