Pharmacological Insights into Medicinal Plants and Phytomolecules for the Management of Alopecia with Mechanistic Perspectives and Therapeutic Potential

    July 2026 in “ Current Pharmaceutical Design
    Pritisha Sadhu, Bhawana Jangra, Alok Goyal, Sanjay M. Jachak
    TLDR Plant-based treatments like Eclipta alba and Ginkgo biloba may help with hair loss and could be safer than synthetic options.
    This review consolidates current knowledge on synthetic agents and medicinal plants for alopecia treatment, highlighting the therapeutic potential of plants like Eclipta alba and Ginkgo biloba. These plants exhibit anti-alopecia activity through mechanisms such as 5-α reductase inhibition and Wnt/β-catenin pathway activation. Key phytoconstituents include flavonoids and terpenoids. The review suggests that plant-based therapeutics could be safer alternatives or adjuncts to synthetic treatments, but emphasizes the need for further clinical trials and standardization to confirm their efficacy and safety.
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