Pharmacy Boa Hora - Porto
November 2025
in “
Open Repository of the University of Porto (University of Porto)
”
TLDR Minoxidil and spironolactone can improve hair growth, but responses vary and side effects are common.
Ana Margarida de Oliveira Rito's internship report at Farmácia da Boa Hora highlights her involvement in preparing a 5% minoxidil solution for alopecia androgenética, emphasizing the importance of good manufacturing practices for effective hair growth treatments. The report also discusses spironolactone's potential as an off-label treatment for female androgenetic alopecia (AAF), noting moderate to significant improvements in hair density and diameter, especially when combined with minoxidil. However, individual responses vary, and side effects like menstrual irregularities are common. The document underscores the need for personalized treatment plans and continuous monitoring, with a call for larger, long-term studies to confirm the efficacy and safety of spironolactone, particularly in topical formulations.