Phenotypic Characterization of Patients with Polycystic Ovary Syndrome in a Population from the Ecuadorian Andes: A Cross-Sectional Study

    April 2024 in “ Journal of clinical medicine ”
    María Elena Espinosa, Raúl Sánchez, Támara Otzen, Estefanía Bautista-Valarezo, Stephanie Aguiar, Isabel Corrales Gutiérrez, Fátima León-Larios, Carlos Manterola
    TLDR Classical PCOS types A and B are most common and linked to higher health risks.
    This cross-sectional study characterized 92 women with Polycystic Ovary Syndrome (PCOS) from the Ecuadorian Andes, identifying phenotypes A and B as the most common and severe, associated with higher risks of oligomenorrhea, hypertriglyceridemia, and elevated HbA1c and AMH levels. Phenotypes A and B also showed higher, though not statistically significant, prevalence of acne, acanthosis nigricans, hirsutism, and elevated total testosterone. The study underscores the need for personalized PCOS management due to the clinical and metabolic variability among phenotypes, while noting limitations such as a small sample size and lack of a control group.
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