The Pilocutaneous Syndrome of Menopause

The document introduces the concept of the pilocutaneous syndrome of menopause (PSM), which encompasses various skin and hair changes associated with menopause. These changes include skin barrier dysfunction, xerosis (dry skin), dermal thinning and laxity, pigmentary dysregulation, female pattern hair loss, hirsutism, and inflammatory acne. The study emphasizes the importance of recognizing these estrogen- and androgen-driven changes, which have been less formally acknowledged compared to other menopause-related syndromes like the genitourinary and musculoskeletal syndromes. The authors conducted a comprehensive literature review to define PSM and propose a framework for its recognition, diagnosis, and treatment.