Low Molecular Weight Porcine Placenta Peptide (Placenderm®) as a Functional Ingredient for Hair Health: Evidence from In Vitro and In Vivo Studies

September 2025 in “ Food Science and Biotechnology ”

Chaerin Lee, Ja Seung Koo, Jinhak Kim, Yuri Gwon, Won‐Chul Lim, Tae‐Gyu Lim

low molecular weight porcine placenta peptides Placenderm human dermal papilla cells anagen phase hair follicle characteristics follicular regeneration

TLDR Placenderm® can improve hair health and promote hair regrowth.

The study investigates the effects of low molecular weight porcine placenta peptides (Placenderm®) on hair health, revealing that Placenderm® enhances cell proliferation and modulates gene expression in human dermal papilla cells. In vivo experiments with C57BL/6 mice showed accelerated hair regrowth, extended anagen phase, and improved hair follicle characteristics. These findings suggest that Placenderm® can promote follicular regeneration and may serve as a functional food ingredient for improving hair health.

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