Protein-Losing Enteropathy Exacerbated with the Appearance of Symptoms of Systemic Lupus Erythematosus

    January 2001 in “ Internal Medicine ”
    Minako Yoshida, Masayuki Miyata, Mitsuru Saka, Tomomi Sasajima, Hiroshi Satō, Junko Takiguchi, Hideo Shishido, Ayako Saito, Masae Kokubun, Tomoe Nishimaki, Reiji Kasukawa
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    TLDR Protein-losing enteropathy worsened with lupus symptoms but improved with prednisolone.
    A 38-year-old woman experienced symptoms such as edema, diarrhea, polyarthralgia, Raynaud's phenomenon, malar rash, and hair loss, leading to a diagnosis of protein-losing enteropathy (PLE) associated with systemic lupus erythematosus (SLE). Her condition was confirmed through 99mtechnetium-labeled human serum albumin scintigraphy and laboratory tests for antinuclear and anti-Sm antibodies. The case highlighted a strong link between PLE and SLE, as PLE worsened with the onset of SLE symptoms but improved with prednisolone treatment, which also alleviated SLE symptoms.
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