Preclinical Evidence and Underlying Mechanisms of Polygonum Multiflorum and Its Chemical Constituents Against Cognitive Impairments and Alzheimer’s Disease

The review compiles current experiments on Alzheimer's Disease (AD) and cognitive impairment models, focusing on the therapeutic effects of Polygonum multiflorum. It highlights the potential of this plant and its chemical constituents in treating neurological disorders, suggesting that these findings could inform future clinical trials. The review emphasizes the promise of Polygonum multiflorum in addressing cognitive impairments and AD, providing a foundation for further research in human applications.