Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution

    June 1994 in “ Archives of Dermatology ”
    Steven Kossard
    TLDR Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.
    The study examined six postmenopausal women who developed progressive frontal fibrosing alopecia, characterized by recession of the frontal hairline with perifollicular erythema and fibrosis. Scalp biopsies revealed lymphocytic inflammation, predominantly activated T-helper cells, around the follicles. Unlike typical lichen planopilaris, these women did not have mucous membrane or skin lesions, and hormonal studies showed no elevated androgen levels. The findings suggested that this form of alopecia might be a distinct reaction pattern associated with postmenopausal changes rather than a typical scarring alopecia like lichen planopilaris.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 656 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community can someone help me identify these pls

      in Treatment 3 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  123 upvotes 4 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 1 year ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

    Related Research

    7 / 7 results