Postmenopausal Ovarian Hyperandrogenism of Surgically Treated Patients: A Case Report and Scoping Review with Individual Patient's Data Analysis

August 2025 in “ Frontiers in Endocrinology ”

A Forte, Lanfranco D’Elia, Cristina Luca, Antonella Fiore, Antonio Barbato, Veronica Abate, Anita Vergatti, Nunzia Verde, Gianpaolo De Filippo, Pietro Venetucci, Maria Chiara De Angelis, Rosa Maria Di Crescenzo, Fortunata Grasso, Giuseppe Pascarella, Pietro Formisano, Attilio Di Spiezio Sardo, Rosario Pivonello, Domenico Rendina

postmenopausal ovarian hyperandrogenism ovarian tumors biochemical parameters androgens

TLDR Biochemical markers help diagnose ovarian tumors in postmenopausal women.

The document discusses postmenopausal ovarian hyperandrogenism (oPH) and provides biochemical parameters that aid in diagnosing ovarian tumors in affected patients. Through a case report and scoping review, the study highlights the importance of these parameters in identifying oPH, which can lead to more accurate diagnoses and treatment plans for surgically treated patients. The analysis of individual patient data further supports the utility of these biochemical markers in clinical settings.

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Research cited in this study

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research Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women: What Is the Evidence?

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research Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman

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Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

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Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

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research Androgenic Hormone Profile of Adult Women with Acne

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