Use of Povidone Iodine Plus Diode Laser for Treatment of Infected Wounds in Mice

The study evaluated the effects of 660 nm diode laser treatment, povidone iodine, and their combination on infected wounds in 40 mice. The results showed that the diode laser alone effectively eliminated Pseudomonas aeruginosa infection and significantly enhanced wound healing, with wounds becoming barely visible by day 14. Povidone iodine also eradicated the infection but slightly delayed healing compared to the laser. The combination of povidone iodine and laser treatment synergistically improved wound healing and infection control, with complete epithelialization and normal skin structure observed by day 14.