Premature Graying of Hair: A Comprehensive Review and Recent Insights

August 2024 in “ Indian Dermatology Online Journal ”

Kavita Poonia, Mala Bhalla

premature graying of hair oxidative stress antioxidant treatments gene therapy nutritional deficiencies

TLDR Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.

This comprehensive review explores the various causes and mechanisms behind premature graying of hair (PMGH), identifying genetic factors, oxidative stress, and environmental influences as key contributors. It highlights risk factors such as family history, smoking, and nutritional deficiencies. The review also discusses the psychosocial effects of PMGH, noting its impact on self-esteem and social interactions. Emerging therapies are examined, including antioxidant treatments and gene therapy, which show promise in addressing the underlying causes of PMGH. The review emphasizes the need for further research to develop effective interventions for this condition.

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