PRIDE Syndrome: A Practical Way to Identify Adverse Skin Effects of EGFR Inhibitors

    October 2021 in “ Revista Medicina Cutánea Ibero-Latino-Americana ”
    Paula Johana Barba, Lucía Piccinelli, Betina De Andrés, Mariana Hurtado
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    TLDR PRIDE syndrome helps identify skin side effects from EGFR inhibitors like erlotinib.
    The document discussed the PRIDE syndrome, which was a practical way to identify adverse skin effects associated with the use of epidermal growth factor receptor (EGFR) inhibitors, such as erlotinib. These dermatological side effects included pruritic papulopustular eruptions, xerosis, paronychia, and non-scarring diffuse alopecia. These conditions could be bothersome and disabling, but timely intervention improved patients' quality of life and adherence to treatment. The document presented a case of a patient who developed these symptoms after starting treatment with erlotinib.
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