The Efficiency of Platelet-Rich Plasma in Treating Post-Burn and Surgical Scars: A Meta-Analysis Study

    November 2025 in “ Journal of Clinical Medicine ”
    Ziyad Alharbi, Tala Zafar
    TLDR PRP may help reduce scar symptoms like pain and itching after six months.
    This meta-analysis of 11 randomized controlled trials with 539 participants evaluated the efficacy of platelet-rich plasma (PRP) in treating post-burn and surgical scars. While individual trials showed some improvements with PRP, the pooled data did not reveal statistically significant changes in scar appearance at three months. However, there was a significant improvement in patient-reported outcomes at six months, indicating PRP's potential in reducing symptoms like pain, itching, and stiffness. The study highlights the need for standardized PRP protocols and longer follow-up periods, suggesting that PRP may be beneficial in early postoperative wound healing, but further research is needed to determine its effectiveness on mature scars.
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