PSAT1 Regulates Hair Follicle Growth and Stem Cell Behavior in Cashmere Goats

    April 2025 in “ BMC Veterinary Research
    Xiaoyu Han, Jia‐Ning Liu, Nina Sun, Y Zhang, Hong Bai, Weiguo Song, Xiao Hu, Hao Liang, Miao Xiong, Yang He, Dongjun Liu, Xudong Guo
    TLDR PSAT1 is key for hair growth and stem cell function in cashmere goats.
    The study identifies PSAT1 as a crucial regulator of secondary hair follicle stem cell (SHFSC) function in cashmere goats, influencing both cell survival and their ability to regenerate. By modulating various signaling pathways, PSAT1 significantly impacts the secondary hair follicle cycle, suggesting its potential as a molecular target to enhance cashmere fiber production.
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