Rapid Analysis of the Chemical Composition of Xiaoban Kangfu Capsules Using UHPLC-Q-Exactive Orbitrap MS/MS and Molecular Networks

    March 2026 in “ Pharmaceuticals
    Xia Luo, Yuehan Liao, Ting Qing, Jihui Zhao, Wei Cai
    TLDR Xiaoban Kangfu capsules contain compounds that may help with antioxidants, reducing inflammation, and promoting hair growth.
    The study conducted a comprehensive analysis of the chemical composition of Xiaoban Kangfu (XBKF) capsules using UHPLC-Q-Exactive Orbitrap MS/MS combined with molecular network analysis, identifying 170 compounds, including flavonoids, phenolic acids, and terpenoids. This method improves the accuracy of chemical profiling and offers a promising approach for quality control. The research highlights the pharmacological activities of the capsules, such as antioxidant, anti-inflammatory, and hair growth-promoting effects, and suggests potential for discovering novel compounds. The findings provide a foundation for further research on the quality control and development of modern XBKF capsule prescriptions.
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