Rare Conditions of Hyperandrogenism Through Lifespan: A Case Series

    January 2025 in “ Case Reports in Endocrinology ”
    Maria Apostolopoulou, Robert Taayedi, Cosmin-Paul Sarac, Frank Demtröder
    TLDR Accurate diagnosis of rare hyperandrogenism conditions requires detailed testing and sometimes invasive procedures.
    The case series examines rare conditions of hyperandrogenism in females, beyond the common PCOS, through four cases involving adrenal and ovarian sources. It highlights the diagnostic challenges and management strategies, emphasizing the need for detailed biochemical testing and high clinical suspicion. The study underscores the importance of early diagnosis and treatment to mitigate risks such as diabetes, obesity, and cardiovascular issues. Surgical interventions, such as adrenalectomy and oophorectomy, were effective in improving symptoms like hirsutism and androgenetic alopecia. The findings stress the necessity of individualized treatment plans and long-term follow-up to monitor symptoms and metabolic changes.
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