The Reason for the Palace

    Pere Artís
    TLDR Tooth loss can cause premature gray hair due to less chewing.
    This study investigated the effect of reduced mastication on premature hair graying by extracting maxillary first molars from young mice and observing them for 3 months. The results showed that gray hair appeared in the interbrow region of the tooth extraction group but not in the control group. Additionally, the expression of tyrosinase-related protein-2 (TRP-2) mRNA was lower in the interbrow tissues of mice without maxillary molars. The findings suggested that tooth loss leads to interbrow gray hair growth, possibly due to weakened trigeminal nerve input, indicating that reduced mastication causes premature graying. Prompt prosthetic treatment after molar loss was recommended.
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