A Review on PCOS: Its Causes, Symptoms, Pathogenesis and Management

    Vijay Daulatrao Havaldar, Nilam Yuvraj Jadhav, Snehal S. Shinde, Savita S. Mali, Kailas Krishnat Mali, Aishwarya Atmaram Shinde, Rutuja Amarsing Rajput
    TLDR PCOS management needs patient adherence to treatment.
    Polycystic Ovarian Syndrome (PCOS) is a prevalent endocrine and metabolic condition affecting approximately 116 million women worldwide. It is characterized by symptoms such as insulin resistance, increased testosterone levels, and malfunctioning ovaries. External causes include genetic factors, diet, and environmental influences, while internal causes involve insulin resistance, inflammation, hyperandrogenism, and obesity. Symptoms include irregular periods, hirsutism, acne, mood swings, weight gain, and hair thinning. The pathogenesis involves alterations in insulin secretion and excess androgen levels. Effective management of PCOS requires a focus on patient adherence to treatment.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community My scalp punch biopsy results🤔?

      in Female  8 upvotes 3 years ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community PCOS Hair Loss: What’s Helped Me (and What Didn’t)

      in Treatment  10 upvotes 6 months ago
      OP shares their experience with PCOS-related hair loss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.

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