Reviewing and Exploring the Prospects of Platelet-Rich Plasma (PRP) Therapy in the Context of Pediatric Surgical Wound Management

    Devina Subagio, Ahmad Fawzy
    TLDR PRP therapy may improve healing in children's surgical wounds.
    This review highlights the potential of platelet-rich plasma (PRP) therapy as an adjunctive treatment for pediatric surgical wound care, emphasizing its role in enhancing wound healing through mechanisms like cell proliferation and tissue regeneration. It evaluates the efficacy, mechanisms, and challenges of PRP therapy, including its immunomodulatory effects and interaction with growth factors. The review also discusses clinical outcomes, safety concerns, and adverse effects, providing insights for evidence-based practice. It calls for future research to refine protocols, ensure cost-effectiveness, and integrate PRP therapy into clinical guidelines while adhering to ethical standards.
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