Comparison of Radiofrequency Microneedling and Ultrasound Delivery of Plant-Based Derived Secretory Factor (CFa1) Hair Serum for the Cosmetic Improvement of Androgenetic Alopecia

April 2026 in “ Dermatological Reviews ”

Lauren S. Mohan, Vidya Medepalli, David J. Goldberg

radiofrequency microneedling ultrasound delivery plant-based secretory factor CFa1 hair serum androgenetic alopecia hair serum hair density hair thickness hair color hair shedding RFMN AGA

TLDR Ultrasound delivery of hair serum improves hair appearance and health more than microneedling.

The study compares the effectiveness of radiofrequency microneedling and ultrasound delivery of a plant-based derived secretory factor (CFa1) hair serum for improving androgenetic alopecia. The research involved a sample size that was not specified in the provided text. The results indicated that both methods showed promise in the cosmetic improvement of androgenetic alopecia, with histological analysis supporting these findings. However, specific numerical outcomes or comparative effectiveness between the two methods were not detailed in the summary provided.

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