Assessment of the Role of miR-30a-5p on the Proliferation and Apoptosis of Hair Follicle Stem Cells

    October 2024 in “ Journal of Cosmetic Dermatology
    Yiping Wang, Wentao Wu, Risheng Wang, Jinwei Chen, Xiangping Xu, Meiqi Li, Chiyu Jia, Nian Chen
    TLDR Reducing miR-30a-5p helps hair follicle stem cells grow and survive.
    The study investigates the role of miR-30a-5p in hair follicle stem cells (HFSCs), revealing that downregulation of miR-30a-5p inhibits apoptosis and promotes proliferation of these cells. This effect is associated with an increased expression of β-catenin, indicating the activation of the Wnt/β-catenin signaling pathway, which is crucial for hair follicle development and regeneration.
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