Computational Evaluation of Rosemary Extract (Rosmarinus Officinalis) and Its Bioactive Compounds as Potential Therapeutic Agents for Androgenic Alopecia

This study explores the potential of rosemary extract as a therapeutic agent for androgenic alopecia (AGA) using computational methods. By employing molecular docking techniques, the researchers evaluated the interactions between bioactive compounds in rosemary extract and key proteins associated with AGA, such as the androgen receptor and 5α-reductase. The findings indicate promising binding affinities, suggesting that rosemary extract could modulate these targets, potentially promoting hair growth and preventing hair loss. The study provides a foundation for further in vitro and in vivo research to validate rosemary extract's efficacy in managing AGA, highlighting its potential as a natural alternative to conventional treatments.