Computational Evaluation of Rosemary Extract (Rosmarinus Officinalis) and Its Bioactive Compounds as Potential Therapeutic Agents for Androgenic Alopecia

The study explores the potential of rosemary extract as a treatment for androgenic alopecia (AGA) using computational methods. By employing molecular docking techniques, researchers evaluated the interactions between rosemary's bioactive compounds and key proteins linked to AGA, such as the androgen receptor and 5α-reductase. The findings indicate promising binding affinities, suggesting that rosemary extract could modulate these targets, potentially promoting hair growth and preventing hair loss. This computational analysis lays the groundwork for further in vitro and in vivo studies to confirm rosemary extract's efficacy in managing AGA.