Effect of Rosemary Extract on Some Internal Organs of Young Male Albino Rats: A Histological Study
June 2023
in “
Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ
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The study investigated the effects of rosemary extract on young male albino rats whose mothers were treated with the extract during lactation. The research involved three groups: a control group and two groups treated with 200 mg/kg and 1000 mg/kg doses of rosemary extract. Results showed that a high dose (1000 mg/kg) led to negative health effects in the offspring, including failure to gain weight and atrophic and degenerative changes in the liver and kidney. Additionally, there was a significant reduction in Leydig cells in the testes. The study concluded that high doses of rosemary extract have teratogenic effects and should be avoided during pregnancy and lactation.