S116 Treatment of Concomitant Alopecia Areata and Crohn’s Disease in a Young Child With Tofacitinib: Case Report
December 2024
in “
The American Journal of Gastroenterology
”
This case report describes a 12-year-old patient with Crohn’s disease (CD) and alopecia areata (AA) who responded well to treatment with tofacitinib, a Janus kinase 3 inhibitor. The patient developed AA after receiving infliximab for CD, which did not improve with topical treatments. Upon switching to tofacitinib, the patient experienced significant hair regrowth within 1 month and complete resolution by 8 months, while maintaining clinical remission of CD. This case suggests that tofacitinib is an effective treatment for both AA and CD in pediatric patients, highlighting its potential use in similar cases.