Can Plasma Rich in Growth Factors Be Safe for Parental Use? A Safety Study in the Canine Model

September 2018 in “ International Journal of Molecular Sciences ”

Elena Damiá, Déborah Chicharro, Mónica Rubio, José M. Carrillo, Joaquín J. Sopena, Belén Cuervo, Sergio López, J. M. Vilar

platelet-rich plasma insulin-like growth factor-1 PRP IGF-1

TLDR PRP derivatives are likely safe for therapeutic use without harmful effects.

The study evaluated the safety of plasma rich in growth factors (PRGF) for intramuscular use in 24 healthy Beagle dogs. Researchers found no significant changes in insulin-like growth factor-1 (IGF-1) serum concentrations or muscle size, indicating that PRGF injections did not have systemic or local anabolic effects. The study concluded that PRGF application was safe, as it did not increase IGF-1 levels or cause muscle hypertrophy, even with higher doses. The findings suggested that PRGF could be a safe treatment option without ergogenic or carcinogenic risks, although further research was needed to assess its safety in humans.

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research Platelet-Rich Plasma for the Treatment of Androgenic Alopecia: A Systematic Review

23 citations , June 2018 in “Facial Plastic Surgery”

Platelet-Rich Plasma (PRP) is a low-risk treatment for Androgenic Alopecia (AGA) that generally improves hair count or density, but more research is needed for optimization.

research Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology

113 citations , July 2015 in “Journal of Cosmetic Dermatology”

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

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community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 9 months ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Nice & pure PRP, 3 ml of this is going to the scalp.

in Research/Science 32 upvotes 3 years ago

The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.

community I have successfully stopped my hormone-induced hair loss ( caused by PCOS,) for 2 years now but I can't seem to be able to regrow the lost hair. Has anyone tried Platelet-Rich Plasma Therapy (PRP)?

in Female 8 upvotes 4 years ago

GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2737 upvotes 1 year ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

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Platelet-Rich Plasma: Applications in Cosmetic Medicine and Surgery

research Advantages and Clinical Applications of Lyophilized Platelet-Rich Plasma in Various Disease Conditions: A Review

November 2021 in “International Journal for Research in Applied Science and Engineering Technology”

Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.