Squamous Cell Carcinoma of the Scalp Following Synthetic Hair Implantation: A Structured Narrative Review and the Seventh Case Reported in Literature

Synthetic hair implantation has been associated with rare cases of squamous cell carcinoma (SCC) of the scalp, with the seventh case recently reported involving a 62-year-old male who developed SCC 30 years post-implantation. The review suggests that chronic inflammation and foreign body reactions from synthetic fibers may contribute to carcinogenesis. Surgical excision, reconstruction, and adjuvant radiotherapy were effective, with no relapse after 11 months. The study underscores the necessity for long-term follow-up due to the extended latency period before cancer development, despite no metastasis observed in the seven cases. It calls for larger studies to further explore this potential link.