Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report

This case report details a 29-year-old HIV-positive woman who developed secondary syphilis, presenting with alopecia and leukoderma, despite being on antiretroviral therapy. The patient experienced generalized hair loss and skin depigmentation, which were resolved following treatment with Benzathine Penicillin 2.4MU. The report emphasizes the necessity for healthcare providers to maintain a high level of clinical suspicion for syphilis in patients with atypical symptoms, particularly in resource-limited settings, to ensure accurate diagnosis and effective management. The case also highlights the importance of recognizing diverse clinical manifestations of syphilis in HIV-positive individuals.