Formation Mechanism, Construction, And Performance Evaluation Of Self-Assembled Nanoparticles From Natural Products

    January 2026 in “ PubMed Central
    CHENG Sihan, LI Yutian, LI Xinyue, LUO Shuang, Yin Yaping, WAN Jun, Zhou Xia
    TLDR Natural product nanoparticles improve drug absorption but need better stability and production methods.
    The document explores the formation, construction, and performance of self-assembled nanoparticles (SANs) from natural products, highlighting their improved drug absorption and distribution capabilities. These nanoscale assemblies are created through non-covalent interactions using techniques like nanoprecipitation and emulsion-solvent evaporation, resulting in superior physicochemical properties and drug release performance. However, challenges such as stability and large-scale industrial application persist. Future research should aim to enhance production methods, stability, and investigate their use in targeted and responsive drug delivery systems.
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