High-Throughput Sequencing of Hair Follicle Development-Related MicroRNAs in Cashmere Goat at Various Fetal Periods

    December 2017 in “ Saudi Journal of Biological Sciences ”
    Yang Liu, Lele Wang, Xiaoyan Li, Wenjing Han, Kun Yang, Honghao Wang, Yanjun Zhang, Rui Su, Zhihong Liu, Ruijun Wang, Zhiying Wang, Yanhong Zhao, Zhixin Wang, Jinquan Li
    TLDR Certain microRNAs are crucial for hair follicle development in cashmere goats.
    The study investigated the development of cashmere in Inner Mongolia cashmere goats by analyzing microRNA and mRNA expression in fetal skin samples at 10 different periods. High-throughput sequencing was performed on RNA samples from fetuses at 45, 55, and 65 days, focusing on hair follicle initiation, growth, and development. The results showed that microRNAs in the oar-let-7 and oar-miR-200 families were significantly up-regulated at 55 and 66 days compared to 45 days, suggesting their critical role in hair follicle development.
    Discuss this study in the Community →

    Research cited in this study

    6 / 6 results