Serial Sections of Atrophic Acne Scars Help in the Interpretation of Microscopic Findings and the Selection of Good Therapeutic Modalities

    November 2011 in “ Journal of the European Academy of Dermatology and Venereology ”
    W.J. Lee, Hyun-A Jung, Hyeon-Ji Lim, Yong Hyun Jang, S.‐J. Lee, D.W. Kim
    TLDR Effective acne scar treatment should use combination therapy based on specific skin changes.
    The study examined the microscopic characteristics of 31 atrophic acne scars from 5 patients to aid in selecting effective therapeutic modalities. Serial sections of the scars revealed key features such as keratin plugging in hair follicle orifices (32%), multi-channelled tracts (29%), decreased dermal thickness, loss of pilosebaceous units, and inflammatory cell infiltrates in the dermis (77%). Insufficient dense collagen fiber deposition was noted in 29% of the dermis. The findings suggested that treatment should consider these histopathological insights and potentially involve combination therapy for improved outcomes.
    Discuss this study in the Community →

    Related Community Posts Join

    4 / 4 results

      community Unofficial Dermapen/Roller Guide

      in Treatment  257 upvotes 7 years ago
      Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

    Similar Research

    5 / 1000+ results
      What's New in Cicatricial Alopecia?

      research What's New in Cicatricial Alopecia?

      16 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
      New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
      Primary Scarring Alopecias

      research Primary Scarring Alopecias

      27 citations , January 2015 in “Current problems in dermatology”
      The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
      Acne and Acneiform Eruptions

      research Acne and Acneiform Eruptions

      2 citations , January 2011 in “Elsevier eBooks”
      Early treatment of acne is crucial to prevent scarring and psychological effects.
      Histopathologic Evaluation of Alopecias

      research Histopathologic Evaluation of Alopecias

      90 citations , June 2006 in “The American Journal of Dermatopathology”
      The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.