Severe Iron Deficiency Is Associated With a Reduced Conception Rate in Female Rats

    October 2013 in “ Gynecologic and Obstetric Investigation ”
    Yan Qin Li, Xiao Xiao Cao, Bin Bai, Jing Ni Zhang, Ming Qi Wang, Yao Hui Zhang
    TLDR Severe iron deficiency lowers fertility in female rats.
    This study investigated the impact of severe iron deficiency on conception rates in female rats. Two groups of female rats (n = 15 each) were used: one fed a low iron diet and the other a normal diet. The iron-deficient rats exhibited symptoms such as white skin and eyes, hair loss, and weight loss, along with significantly lower hemoglobin levels and red blood cell counts. The results showed a significantly lower conception rate in the iron-deficient group, along with disruptions in estrus and delays in conception. The study concluded that severe iron deficiency significantly affected fertility and could be a factor in unexplained infertility, suggesting the need for further research on iron's role in conception.
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