Influence of Sex and Functional Status on the Value of Serum Steroid Profiling in Discriminating Adrenocortical Carcinoma from Adrenocortical Adenoma
September 2024
in “
Frontiers in Endocrinology
”
TLDR Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.
Serum steroid profiling is a useful tool for distinguishing between adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA), with 11-deoxycortisol identified as the most significant marker. The study highlights the importance of considering sex differences and functional status when evaluating other steroid hormones for this purpose.