Side Effects and Possible Complications of Oral Contraceptive Drugs

    January 1980 in “ PubMed
    Rossi Gv
    TLDR Oral contraceptives can cause nausea, headaches, mood changes, and other side effects, especially early on.
    The document discussed the side effects and complications associated with oral contraceptive drugs, which were most pronounced during the initial months of use. Common reactions included nausea, dizziness, headache, and depression, often attributed to the estrogenic component. Other side effects reported were breast tenderness, intermenstrual spotting, and breakthrough bleeding, which could be mitigated by increasing dosage. Some users experienced skin reactions, hirsutism, and changes in weight. Serious complications included vascular issues and hepatic dysfunction, with potential thyroid function deviations. Concerns about carcinogenesis were noted, though unproven at the time. The document emphasized the need for further research to assess the long-term safety of oral contraceptives.
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