Data-Driven Visualization of Silica-Based Nanobiomaterial Dynamics for Tissue Regeneration

    January 2026 in “ Microsystems & Nanoengineering ”
    Chao Yang, Z. P. Xie, Sihua Liang, Zhan Liu, Luís Cardoso, Dan Hou, Janak Lal Pathak, Lü Li
    TLDR Research on silica-based nanobiomaterials for tissue regeneration is rapidly growing, with China leading in volume and the U.S. excelling in impact.
    The study systematically analyzed 853 research articles on silica-based nanobiomaterials (SNs) from 2006 to 2025, using bibliometric tools to visualize trends and research hotspots in regenerative medicine. It found a rapid increase in research output, with China leading in volume and the United States excelling in citation impact. Key research areas include drug delivery systems, antimicrobial activity, bone regeneration, and wound healing, with emerging topics like mesoporous bioactive glass nanoparticles and zinc ion dopants. The study highlights disparities in research impact and offers insights into future directions and challenges in the field.
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