Skin Microbiome Shifts in Various Dermatological Conditions

    August 2025 in “ Journal of Clinical Medicine ”
    Chau-Chin Lee, Mildred Min, Shumin Jin, Raja K. Sivamani
    The review highlights significant alterations in the skin microbiome associated with various dermatological diseases, noting a decrease in microbiome diversity and an increase in pro-inflammatory bacterial and fungal strains, particularly Staphylococcus aureus. These changes provide insights into the development and progression of inflammatory skin conditions. The review suggests that prebiotic treatments could offer a safer and more cost-effective alternative to antibiotics, which pose risks of toxicity and antibiotic resistance. However, further research is needed to understand microbiome changes and evaluate the effectiveness of probiotic treatments in restoring the skin microbiome and improving patient outcomes.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 1000+ results

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  414 upvotes 11 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community My progress lmk if you need advice 22 years old

      in Is this regrowth?  189 upvotes 1 year ago
      Minoxidil, finasteride, dutasteride, and copper peptides are discussed as treatments for hair loss, with users sharing experiences and concerns about side effects and effectiveness. Oral minoxidil and dutasteride are suggested for better regrowth, while topical minoxidil caused irritation for some.

      community Scalp, eyebrow, eyelash and pubic hair loss.

       6 upvotes 7 years ago
      The user experienced significant hair loss on the scalp, eyebrows, eyelashes, and pubic area, along with itchy, flaky skin and red patches. They have a history of eczema and dermatitis and suspect that stopping shampoo use and taking Ritalin may have contributed to the issue.

      community My Experience and a Discourse on "DUPA"

      in Treatment  8 upvotes 1 year ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

    Similar Research

    5 / 1000+ results