Skin Stem Cells, Their Niche, and Tissue Engineering Approach for Skin Regeneration

    Nur Kübra Çankirili, Özlem Altundag, Betül Çelebi‐Saltik
    TLDR Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
    The document reviewed the role of skin stem cells and their niche in skin regeneration, emphasizing the potential of tissue engineering approaches. It highlighted the importance of signaling pathways like Wnt, BMP, Hedgehog, and Notch in regulating stem cell behavior and hair follicle development. Various studies on the use of adipose-derived, hair follicle, and mesenchymal stem cells for wound healing and tissue repair were discussed. The review also covered the use of autologous keratinocytes and pericytes in treating nonhealing wounds and skin regeneration. Overall, it underscored significant advancements and future potential in stem cell-based skin regeneration.
    Discuss this study in the Community →

    Research cited in this study

    21 / 21 results

    Related Community Posts Join

    6 / 1000+ results

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  41 upvotes 6 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  232 upvotes 4 months ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A Theory on Why Microneedling Works

       170 upvotes 6 years ago
      Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

    Similar Research

    6 / 1000+ results