A Case of Systemic Lupus Erythematosus with Cutaneous Leukocytoclastic Vasculitis

    January 1984 in “ Japanese Journal of Clinical Immunology ”
    Akira Takeda, Mariko Sasaki, Nagahiro Minato, Yoshiaki Mizoguchi, Morito Sumiya, Shogo Kano, Chieko Watanabe, Yoshihiko Fujieda, Kou Kaneko
    TLDR A woman with lupus developed a rare skin condition, which improved with increased medication.
    This document described a case of a 34-year-old woman with systemic lupus erythematosus (SLE) who developed leukocytoclastic vasculitis, a rare skin condition in SLE patients. Her illness began at age 27 with symptoms like fever, polyarthralgia, and proteinuria, and she was diagnosed with SLE in 1978. Despite being stable on 10 mg of prednisolone, she experienced a flare-up in 1982, leading to erythematous rashes and ulcerations. Laboratory tests showed elevated anti-DNA antibodies and hypocomplementemia. A biopsy confirmed leukocytoclastic vasculitis, and treatment with 40 mg of prednisolone improved her condition. The vasculitis was considered a manifestation of SLE, linked to its exacerbation.
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