Sperm Extraction in Nonmosaic Klinefelter Syndrome Patients: A Case Series and Literature Review

    July 2024 in “ Urology Annals ”
    Khalid Alrabeeah, Abdullah Alkhayal, Sahar Aljumaiah, Mohammad Alghafees, Almohannad K Alqarni, Basel Hakami
    TLDR Younger Klinefelter Syndrome patients have a better chance of successful sperm extraction.
    This study focuses on sperm extraction in nonmosaic Klinefelter Syndrome (KF) patients, a condition characterized by infertility and reduced hair growth due to an extra X chromosome. The retrospective study involved 16 patients who underwent micro-testicular sperm extraction (m-TESE) between 2016 and 2022. The sperm retrieval rate (SRR) observed was slightly lower than what is reported in existing literature. The study found that younger patients had a significantly higher likelihood of successful sperm retrieval, suggesting age as an important factor in the effectiveness of m-TESE for KF patients.
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