Potential Multi-Functional Sprayable Poly(N-Isopropylacrylamide)/Dextran Hydrogel Dressings With Incorporation of Silver Nanowires

This study developed a multifunctional, sprayable hydrogel composed of aminated poly(N‐isopropylacrylamide), dopamine-grafted aldehyde dextran, and silver nanowires, which holds strong potential for wound healing applications. The hydrogel exhibits temperature-responsive behavior, forming a gel at 37°C, and can be sprayed to form an adherent layer on human skin. It demonstrated strong antimicrobial effects against E. coli and S. aureus, as well as antioxidant activity through DPPH scavenging. Cytocompatibility was confirmed using NIH‐3T3 cells, indicating its safety for potential medical use.