Correlations Between Soluble Receptor for Advanced Glycation End Products and Heme Oxygenase-1 in Post-COVID-19 Patients With Telogen Effluvium

This study investigated the relationship between oxidative stress markers and telogen effluvium (TE) in post-COVID-19 patients. It included 90 participants divided into three groups: post-COVID-19 patients with TE, those without hair loss, and healthy controls. The study found that patients with TE had significantly higher levels of soluble receptor for advanced glycation end products (sRAGE) and lower levels of heme oxygenase-1 (HO-1) compared to the other groups. Elevated sRAGE and reduced HO-1 were strongly associated with TE severity and were independent predictors of TE. These findings suggest that oxidative stress and impaired antioxidant defense play a crucial role in post-COVID-19 TE, and these biomarkers could be useful for early diagnosis and monitoring.