Steroid Cell Tumor Without Virilization

This case report described a rare instance of a steroid cell tumor of the ovary in a 22-year-old woman, which did not present with typical virilizing symptoms such as hirsutism or male pattern baldness, despite the tumor's malignant potential. The patient exhibited amenorrhea and unusual findings like osteopenia and underweight. Diagnostic imaging revealed a large pelvic mass with metastasis to the liver. Laboratory tests showed normal levels of testosterone and DHEA-S, but elevated serum LDH and AFP levels. Histopathological evaluation confirmed a steroid cell tumor with high malignant potential, characterized by size greater than 7 cm, necrosis, and nuclear atypia. Immunohistochemistry supported the diagnosis, showing positive staining for Inhibin and negative for EMA. The patient underwent debulking surgery followed by adjuvant chemotherapy due to residual disease and elevated markers. The study highlighted the importance of comprehensive hormonal evaluation and pathological assessment in diagnosing and managing such tumors.