Electrospun Nanofibers Containing Strontium for Bone Tissue Engineering

    October 2020 in “ Journal of Nanomaterials
    Qi Zhang, Yanjing Ji, Weiping Zheng, Mingzhe Yan, Danyang Wang, Min Li, Junbo Chen, Yan Xiao, Qiang Zhang, Xiao Yuan, Qihui Zhou
    TLDR Strontium nanofibers can help repair and regenerate bones.
    The document reviewed the potential of electrospun nanofibers containing strontium (Sr) for bone tissue engineering, emphasizing their ability to promote osteogenesis and inhibit osteoclastogenesis. Sr-doped nanofibers improved mechanical properties and biological responses, enhancing bone regeneration and repair. They mimicked the natural bone ECM, supported cell growth and differentiation, and served as drug delivery systems with sustained release and antibacterial properties. In vivo studies confirmed their effectiveness, but further research was needed to determine the optimal Sr concentration to maximize benefits and minimize side effects.
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